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Real time genetic compensation defines the dynamic demands of feedback control

Biological signaling networks use feedback control to dynamically adjust their operation in real time. Traditional static genetic methods such as gene knockouts or rescue experiments often can identify the existence of feedback interactions, yet are unable to determine what feedback dynamics are req...

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Bibliografiska uppgifter
I publikationen:Cell
Huvudupphovsmän: Harrigan, Patrick, Madhani, Hiten D., El-Samad, Hana
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258208/
https://ncbi.nlm.nih.gov/pubmed/30340045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.044
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