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ABT-737 promotes the dislocation of ER luminal proteins to the cytosol, including Pseudomonas exotoxin
Impaired apoptosis is often a key element in tumor development. Therefore, drugs mimicking prosurvival antagonists offer promise as cancer therapeutics. When ABT-737, a BH3-only mimetic, was added to KB3-1 human cervical adenocarcinoma cells we noted an induction of an Endoplasmic Reticulum (ER) str...
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| Publicat a: | Mol Cancer Ther |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6258188/ https://ncbi.nlm.nih.gov/pubmed/24739394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0998 |
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