Brain hyperserotonemia causes autism-relevant social deficits in mice

BACKGROUND: Hyperserotonemia in the brain is suspected to be an endophenotype of autism spectrum disorder (ASD). Reducing serotonin levels in the brain through modulation of serotonin transporter function may improve ASD symptoms. METHODS: We analyzed behavior and gene expression to unveil the causa...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Autism
Main Authors: Tanaka, Miho, Sato, Atsushi, Kasai, Shinya, Hagino, Yoko, Kotajima-Murakami, Hiroko, Kashii, Hirofumi, Takamatsu, Yukio, Nishito, Yasumasa, Inagaki, Masumi, Mizuguchi, Masashi, Hall, F. Scott, Uhl, George R., Murphy, Dennis, Sora, Ichiro, Ikeda, Kazutaka
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258166/
https://ncbi.nlm.nih.gov/pubmed/30498565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-018-0243-3
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