Brain hyperserotonemia causes autism-relevant social deficits in mice

BACKGROUND: Hyperserotonemia in the brain is suspected to be an endophenotype of autism spectrum disorder (ASD). Reducing serotonin levels in the brain through modulation of serotonin transporter function may improve ASD symptoms. METHODS: We analyzed behavior and gene expression to unveil the causa...

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Detalhes bibliográficos
Publicado no:Mol Autism
Main Authors: Tanaka, Miho, Sato, Atsushi, Kasai, Shinya, Hagino, Yoko, Kotajima-Murakami, Hiroko, Kashii, Hirofumi, Takamatsu, Yukio, Nishito, Yasumasa, Inagaki, Masumi, Mizuguchi, Masashi, Hall, F. Scott, Uhl, George R., Murphy, Dennis, Sora, Ichiro, Ikeda, Kazutaka
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258166/
https://ncbi.nlm.nih.gov/pubmed/30498565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-018-0243-3
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