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Distinct roles for Blimp-1 in autoreactive CD4 T cells during priming and effector phase of autoimmune encephalomyelitis

B lymphocyte-induced maturation protein (Blimp-1) is a transcription factor that regulates effector/memory B cells and CD8 T cells. Here we show that Blimp-1 is expressed in both Th1 and Th17 cells in vitro and highly expressed in effector/memory myelin-specific CD4 T cells in experimental autoimmun...

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Bibliografiske detaljer
Udgivet i:J Neuroimmunol
Main Authors: Aqel, Saba I, Granitto, Marissa C, Nuro-Gyina, Patrick K, Pei, Wei, Liu, Yue, Lovett-Racke, Amy E., Racke, Michael K., Yang, Yuhong
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258060/
https://ncbi.nlm.nih.gov/pubmed/30366205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2018.10.007
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