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Preparation of 16β-Estradiol Derivative Libraries as Bisubstrate Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 Using the Multidetachable Sulfamate Linker

Combinatorial chemistry is a powerful tool used to rapidly generate a large number of potentially biologically active compounds. In our goal to develop bisubstrate inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) that interact with both the substrate (estrone or estradiol) and the co...

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Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijät: Bérubé, Marie, Delagoutte, Florian, Poirier, Donald
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Molecular Diversity Preservation International 2010
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257402/
https://ncbi.nlm.nih.gov/pubmed/20336003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15031590
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