Crucial Role of 3-Bromoethyl in Removing the Estrogenic Activity of 17β-HSD1 Inhibitor 16β-(m-Carbamoylbenzyl)estradiol

Por Maltais, René, Ayan, Diana, Poirier, Donald
Publicado em 2011

Structure-Based Design and Synthesis of New Estrane–Pyridine Derivatives as Cytochrome P450 (CYP) 1B1 Inhibitors

Por Dutour, Raphaël, Cortés-Benítez, Francisco, Roy, Jenny, Poirier, Donald
Publicado no ACS Med Chem Lett (2017)

The Aminosteroid Derivative RM-133 Shows In Vitro and In Vivo Antitumor Activity in Human Ovarian and Pancreatic Cancers

Por Kenmogne, Lucie Carolle, Ayan, Diana, Roy, Jenny, Maltais, René, Poirier, Donald
Publicado no PLoS One (2015)

17β-Hydroxysteroid Dehydrogenase Type 1 Stimulates Breast Cancer by Dihydrotestosterone Inactivation in Addition to Estradiol Production

Por Aka, Juliette A., Mazumdar, Mausumi, Chen, Chang-Qing, Poirier, Donald, Lin, Sheng-Xiang
Publicado no Mol Endocrinol (2010)

Synergistic control of sex hormones by 17β-HSD type 7: a novel target for estrogen-dependent breast cancer

Por Wang, Xiaoqiang, Gérard, Catherine, Thériault, Jean-François, Poirier, Donald, Doillon, Charles J., Lin, Sheng-Xiang
Publicado no J Mol Cell Biol (2015)

Investigation of the In Vitro and In Vivo efficiency of RM-532-105, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, in LAPC-4 prostate cancer cell and tumor models

Por Kenmogne, Lucie Carolle, Roy, Jenny, Maltais, René, Rouleau, Mélanie, Neveu, Bertrand, Pouliot, Frédéric, Poirier, Donald
Publicado no PLoS One (2017)

The Intraovarian Actions of Estrogen Receptor-α (ERα) are Necessary to Repress the Formation of Morphological and Functional Leydig-like Cells in the Female Gonad

Por COUSE, JOHN F., YATES, MARIANA M., RODRIGUEZ, KARINA F., JOHNSON, JO ANNE, POIRIER, DONALD, KORACH, KENNETH S.
Publicado em 2006

Estrogen receptor-α mediates an intraovarian negative feedback loop on thecal cell steroidogenesis via modulation of CYP17A1 (cytochrome P450, steroid 17α-hydroxylase/17,20 lyase)...

Por Taniguchi, Fuminori, Couse, John F., Rodriguez, Karina F., Emmen, Judith M. A., Poirier, Donald, Korach, Kenneth S.
Publicado em 2006

8-BuS-ATP derivatives as specific NTPDase1 inhibitors

Por Lecka, Joanna, Gillerman, Irina, Fausther, Michel, Salem, Mabrouka, Munkonda, Mercedes N, Brosseau, Jean-Philippe, Cadot, Christine, Martín-Satué, Mireia, d'Orléans-Juste, Pedro, Rousseau, Éric, Poirier, Donald, Künzli, Beat, Fischer, Bilha, Sévigny, Jean
Publicado em 2013