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The Anti-HIV Actions of 7- and 10-Substituted Camptothecins

Camptothecin (CPT), a traditional anti-tumor drug, has been shown to possess anti-HIV-1 activity. To increase the antiviral potency, the anti-HIV activities of two CPT derivatives, 10-hydroxy-CPT and 7-hydroxymethyl-CPT, were evaluated in vitro. The therapy index (TI) of CPT, 10-hydroxy-CPT and 7-hy...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Molecules
Main Authors: Li, Yu-Ye, Chen, Shi-Wu, Yang, Liu-Meng, Wang, Rui-Rui, Pang, Wei, Zheng, Yong-Tang
פורמט: Artigo
שפה:Inglês
יצא לאור: Molecular Diversity Preservation International 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256925/
https://ncbi.nlm.nih.gov/pubmed/20110878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15010138
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