The Combination of Fosfomycin plus Meropenem Is Synergistic for Pseudomonas aeruginosa PAO1 in a Hollow-Fiber Infection Model

Treating high-density bacterial infections is a challenging clinical problem. We have a paucity of new agents that can address this problem. Pseudomonas aeruginosa is a particularly difficult pathogen to treat effectively because of the plethora of resistance mechanisms it carries. Fosfomycin is an...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Drusano, G. L., Neely, M. N., Yamada, W. M., Duncanson, Brandon, Brown, David, Maynard, Michael, Vicchiarelli, Michael, Louie, Arnold
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256766/
https://ncbi.nlm.nih.gov/pubmed/30249700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01682-18
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