Stereoselective Synthesis of the Isomers of Notoincisol A: Assigment of the Absolute Configuration of this Natural Product and Biological Evaluation

[Image: see text] The total syntheses of all stereoisomers of notoincisol A, a recently isolated natural product with potential anti-inflammatory activity, are reported. The asymmetric synthesis was conducted employing a lipase-mediated kinetic resolution, which enables easy access to all required c...

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Publicado en:J Nat Prod
Main Authors: Rycek, Lukas, Ticli, Vincenzo, Pyszkowski, Jakob, Latkolik, Simone, Liu, Xin, Atanasov, Atanas G., Steinacher, Theresa, Bauer, Rudolf, Schuster, Daniela, Dirsch, Verena M., Schnürch, Michael, Ernst, Margot, Mihovilovic, Marko D.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society and American Society of Pharmacognosy 2018
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256351/
https://ncbi.nlm.nih.gov/pubmed/30362739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.8b00439
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