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Therapeutic Targeting of IRFs: Pathway-Dependence or Structure-Based?

The interferon regulatory factors (IRFs) are a family of master transcription factors that regulate pathogen-induced innate and acquired immune responses. Aberration(s) in IRF signaling pathways due to infection, genetic predisposition and/or mutation, which can lead to increased expression of type...

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Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Thompson, Cherrie D., Matta, Bharati, Barnes, Betsy J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255967/
https://ncbi.nlm.nih.gov/pubmed/30515152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02622
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