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Repurposing CRISPR-Cas12b for mammalian genome engineering
The prokaryotic CRISPR-Cas adaptive immune systems provide valuable resources to develop genome editing tools, such as CRISPR-Cas9 and CRISPR-Cas12a/Cpf1. Recently, CRISPR-Cas12b/C2c1, a distinct type V-B system, has been characterized as a dual-RNA-guided DNA endonuclease system. Though being activ...
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| Publicado no: | Cell Discov |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6255809/ https://ncbi.nlm.nih.gov/pubmed/30510770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41421-018-0069-3 |
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