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CDetection: CRISPR-Cas12b-based DNA detection with sub-attomolar sensitivity and single-base specificity
CRISPR-based nucleic acid detection methods are reported to facilitate rapid and sensitive DNA detection. However, precise DNA detection at the single-base resolution and its wide applications including high-fidelity SNP genotyping remain to be explored. Here we develop a Cas12b-mediated DNA detecti...
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| Udgivet i: | Genome Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6604390/ https://ncbi.nlm.nih.gov/pubmed/31262344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1742-z |
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