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IKKβ activates p53 to promote cancer cell adaptation to glutamine deprivation

One of the hallmarks of cancer is the ability to reprogram cellular metabolism to increase the uptake of necessary nutrients such as glucose and glutamine. Driven by oncogenes, cancer cells have increased glutamine uptake to support their highly proliferative nature. However, as cancer cells continu...

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Bibliografiske detaljer
Udgivet i:Oncogenesis
Main Authors: Ishak Gabra, Mari B., Yang, Ying, Lowman, Xazmin H., Reid, Michael A., Tran, Thai Q., Kong, Mei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255781/
https://ncbi.nlm.nih.gov/pubmed/30478303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0104-0
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