IL-4-dependent Jagged1 expression/processing is associated with survival of chronic lymphocytic leukemia cells but not with Notch activation

As previously reported, chronic lymphocytic leukemia (CLL) cells show constitutive Notch1/2 activation and express the Notchligand Jagged1. Despite increasing knowledge of the impact of Notch alterations on CLL biology and pathogenesis, the role of Jagged1 expressed in CLL cells remains undefined. I...

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Bibliografiset tiedot
Julkaisussa:Cell Death Dis
Päätekijät: De Falco, Filomena, Del Papa, Beatrice, Baldoni, Stefano, Sabatini, Rita, Falzetti, Franca, Di Ianni, Mauro, Martelli, Maria Paola, Mezzasoma, Federica, Pelullo, Maria, Marconi, Pierfrancesco, Sportoletti, Paolo, Screpanti, Isabella, Rosati, Emanuela
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255763/
https://ncbi.nlm.nih.gov/pubmed/30478302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1185-6
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