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Synthesis and Antitumor Activities of Phenanthrene-Based Alkaloids

A series of phenanthrene-based tylophorine derivatives (PBTs) were synthesized and their cytotoxic activities against the H460 human large-cell lung carcinoma cell line were evaluated. Among these compounds, N-(3-hydroxy-2,6,7-tri-methoxyphenanthr-9-ylmethyl)-l-prolinol (5a), and N-(3-hydroxy-2,6,7-...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Li, Songtao, Han, Li, Sun, Liang, Zheng, Dan, Liu, Jiang, Fu, Yingbo, Huang, Xueshi, Wang, Zhanyou
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255436/
https://ncbi.nlm.nih.gov/pubmed/20032876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules14125042
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