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Evolution of weak cooperative interactions for biological specificity

A hallmark of biological systems is that particular functions and outcomes are realized in specific contexts, such as when particular signals are received. One mechanism for mediating specificity is described by Fisher’s “lock and key” metaphor, exemplified by enzymes that bind selectively to a part...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gao, Ang, Shrinivas, Krishna, Lepeudry, Paul, Suzuki, Hiroshi I., Sharp, Phillip A., Chakraborty, Arup K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255166/
https://ncbi.nlm.nih.gov/pubmed/30404915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1815912115
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