639. Indoleamine 2,3 Dioxygenase, Age, and Chronic Immune Activation in HIV Patients

BACKGROUND: Immune activation complicates HIV despite antiretroviral therapy (ART). Indoleamine 2,3 dioxygenase (IDO) catabolizes tryptophan (T) to kynurenine (K), regulating immune activity. IDO activity increases in HIV patients and non-HIV patients with age. This study examines the relationship o...

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Publicado en:Open Forum Infect Dis
Main Authors: Baer, Stephanie, Colombo, Rhonda, Johnson, Maribeth, Wakade, Sushama, Pacholczyk, Gabriela, Thompson, Stuart, Huang, Lei, Saag, Michael, Mellor, Andrew
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255015/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.646
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