Indoleamine 2,3 dioxygenase, age, and immune activation in people living with HIV

Immune activation complicates HIV despite antiretroviral therapy (ART). Indoleamine 2,3 dioxygenase (IDO) catabolizes tryptophan (T) to kynurenine (K), regulating immune activity, and IDO activity increases with age. This study examines the relationship of IDO activity, bacterial translocation, and...

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Publicat a:J Investig Med
Autors principals: Baer, Stephanie L, Colombo, Rhonda E, Johnson, Maribeth H, Wakade, Sushama, Pacholczyk, Gabriela, Newman-Whitlow, Cheryl, Thompson, Stuart A, Saag, Michael S, Martin, Jeffrey N, Floris-Moore, Michelle, Huang, Lei, Mellor, Andrew L
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319090/
https://ncbi.nlm.nih.gov/pubmed/33875612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jim-2021-001794
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