Indoleamine 2,3 dioxygenase, age, and immune activation in people living with HIV

Immune activation complicates HIV despite antiretroviral therapy (ART). Indoleamine 2,3 dioxygenase (IDO) catabolizes tryptophan (T) to kynurenine (K), regulating immune activity, and IDO activity increases with age. This study examines the relationship of IDO activity, bacterial translocation, and...

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Bibliografiske detaljer
Udgivet i:J Investig Med
Main Authors: Baer, Stephanie L, Colombo, Rhonda E, Johnson, Maribeth H, Wakade, Sushama, Pacholczyk, Gabriela, Newman-Whitlow, Cheryl, Thompson, Stuart A, Saag, Michael S, Martin, Jeffrey N, Floris-Moore, Michelle, Huang, Lei, Mellor, Andrew L
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319090/
https://ncbi.nlm.nih.gov/pubmed/33875612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jim-2021-001794
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