Sepsis Induces a Long-Lasting State of Trained Immunity in Bone Marrow Monocytes

Innate immune memory describes the functional reprogramming of innate immune cells after pathogen contact, leading to either a boosted (trained immunity) or a diminished (immune tolerance) response to a secondary stimulus. Immune tolerance or “sepsis-induced immunosuppression” is a typical hallmark...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Bomans, Katharina, Schenz, Judith, Sztwiertnia, Isabella, Schaack, Dominik, Weigand, Markus Alexander, Uhle, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254543/
https://ncbi.nlm.nih.gov/pubmed/30510555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02685
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