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Paternal sepsis induces alterations of the sperm methylome and dampens offspring immune responses—an animal study
BACKGROUND: Sepsis represents the utmost severe consequence of infection, involving a dysregulated and self-damaging immune response of the host. While different environmental exposures like chronic stress or malnutrition have been well described to reprogram the germline and subsequently offspring...
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| Publicado no: | Clin Epigenetics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6022485/ https://ncbi.nlm.nih.gov/pubmed/29988283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-018-0522-z |
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