2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity

2-Hydroxy-oleic acid (2OHOA) is a potent anticancer drug that induces cancer cell cycle arrest and apoptosis. Previous studies have suggested that 2OHOA's anticancer effect is mediated by SMS activation in cancer cells, including A549 and U118 cells. To confirm this phenomenon, in this study, w...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Lou, Bin, Liu, Qi, Hou, Jiahui, Kabir, Inamul, Liu, Peipei, Ding, Tingbo, Dong, Jibin, Mo, Mingguang, Ye, Deyong, Chen, Yang, Bui, Hai H., Roth, Kenneth, Cao, Yu, Jiang, Xian-Cheng
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Lipids
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254338/
https://ncbi.nlm.nih.gov/pubmed/30305392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005904
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