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The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2

Germ cell proliferation is epigenetically controlled, mainly through DNA methylation and histone modifications. However, the pivotal epigenetic regulators of germ cell self-renewal and differentiation in postnatal testis are still poorly defined. The histone methyltransferase enhancer of zeste homol...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Ferreira, Mónica, Verbinnen, Iris, Fardilha, Margarida, Van Eynde, Aleyde, Bollen, Mathieu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254331/
https://ncbi.nlm.nih.gov/pubmed/30305391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC118.005577
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