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The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2

Germ cell proliferation is epigenetically controlled, mainly through DNA methylation and histone modifications. However, the pivotal epigenetic regulators of germ cell self-renewal and differentiation in postnatal testis are still poorly defined. The histone methyltransferase enhancer of zeste homol...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ferreira, Mónica, Verbinnen, Iris, Fardilha, Margarida, Van Eynde, Aleyde, Bollen, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254331/
https://ncbi.nlm.nih.gov/pubmed/30305391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC118.005577
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