The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis

NIPP1 is one of the major nuclear interactors of protein phosphatase PP1. The deletion of NIPP1 in mice is early embryonic lethal, which has precluded functional studies in adult tissues. Hence, we have generated an inducible NIPP1 knockout model using a tamoxifen-inducible Cre recombinase transgene...

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Foilsithe in:Sci Rep
Main Authors: Ferreira, Mónica, Boens, Shannah, Winkler, Claudia, Szekér, Kathelijne, Verbinnen, Iris, Van Eynde, Aleyde, Fardilha, Margarida, Bollen, Mathieu
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2017
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645368/
https://ncbi.nlm.nih.gov/pubmed/29042623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13809-y
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