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The protein phosphatase 1 regulator NIPP1 is essential for mammalian spermatogenesis

NIPP1 is one of the major nuclear interactors of protein phosphatase PP1. The deletion of NIPP1 in mice is early embryonic lethal, which has precluded functional studies in adult tissues. Hence, we have generated an inducible NIPP1 knockout model using a tamoxifen-inducible Cre recombinase transgene...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ferreira, Mónica, Boens, Shannah, Winkler, Claudia, Szekér, Kathelijne, Verbinnen, Iris, Van Eynde, Aleyde, Fardilha, Margarida, Bollen, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5645368/
https://ncbi.nlm.nih.gov/pubmed/29042623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-13809-y
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