The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2

Germ cell proliferation is epigenetically controlled, mainly through DNA methylation and histone modifications. However, the pivotal epigenetic regulators of germ cell self-renewal and differentiation in postnatal testis are still poorly defined. The histone methyltransferase enhancer of zeste homol...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Ferreira, Mónica, Verbinnen, Iris, Fardilha, Margarida, Van Eynde, Aleyde, Bollen, Mathieu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2018
Gaiak:
Accelerated Communications
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6254331/
https://ncbi.nlm.nih.gov/pubmed/30305391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC118.005577
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