2063. Extracellular Release of β-Lactamase Is Responsible for the Cefazolin Inoculum Effect (CzIE) in Methicillin-Susceptible Staphylococcus aureus

BACKGROUND: Cefazolin is becoming first-line therapy for MSSA infections since it appears to be better tolerated than isoxazolyl penicillins with similar outcomes. An important concern when using cephalosporins as first-line therapy for MSSA is the CzIE, defined as MICs ≥ 16 µg/mL when performed at...

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Publié dans:Open Forum Infect Dis
Auteurs principaux: Carvajal, Lina P, Santiago, Alec, Echeverri, Aura, Rios, Rafael, Rincon, Sandra, Panesso, Diana, Diaz, Lorena, Miller, William, Sun, Zhizheng, Palzkill, Timothy, Arias, Cesar, Reyes, Jinnethe
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6253809/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.1719
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