Novel Insights into the Classification of Staphylococcal β-Lactamases in Relation to the Cefazolin Inoculum Effect

Cefazolin has become a prominent therapy for methicillin-susceptible Staphylococcus aureus (MSSA) infections. However, an important concern is the cefazolin inoculum effect (CzIE), a phenomenon mediated by staphylococcal β-lactamases. Four variants of staphylococcal β-lactamases have been described...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Carvajal, Lina P., Rincon, Sandra, Echeverri, Aura M., Porras, Jessica, Rios, Rafael, Ordoñez, Karen M., Seas, Carlos, Gomez-Villegas, Sara I., Diaz, Lorena, Arias, Cesar A., Reyes, Jinnethe
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2020
Ämnen:
Mechanisms of Resistance
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7179603/
https://ncbi.nlm.nih.gov/pubmed/32071048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02511-19
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