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Beyond Type 1 Regulatory T Cells: Co-expression of LAG3 and CD49b in IL-10-Producing T Cell Lineages

Type 1 regulatory CD4(+) T (Tr1) cells express high levels of the immunosuppressive cytokine IL-10 but not the master transcription factor Foxp3, and can suppress inflammation and promote immune tolerance. In order to identify and obtain viable Tr1 cells for research and clinical applications, co-ex...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Huang, Weishan, Solouki, Sabrina, Carter, Chavez, Zheng, Song-Guo, August, Avery
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252342/
https://ncbi.nlm.nih.gov/pubmed/30510554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02625
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