Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation

BACKGROUND: Atrial fibrillation (AF) is frequently associated with enhanced inflammatory response. The “NACHT, LRR and PYD domain containing protein 3” (NLRP3)-inflammasome mediates caspase-1 activation and interleukin-1β release in immune cells, but is not known to play a role in cardiomyocytes (CM...

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Publicado no:Circulation
Main Authors: Yao, Chunxia, Veleva, Tina, Scott, Larry, Cao, Shuyi, Li, Luge, Chen, Gong, Jeyabal, Prince, Pan, Xiaolu, Alsina, Katherina M., Abu-Taha, Issam, Ghezelbash, Shokoufeh, Reynolds, Corey L., Shen, Ying H., LeMaire, Scott A., Schmitz, Wilhelm, Müller, Frank U., El-Armouche, Ali, Eissa, N. Tony, Beeton, Christine, Nattel, Stanley, Wehrens, Xander H.T., Dobrev, Dobromir, Li, Na
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252285/
https://ncbi.nlm.nih.gov/pubmed/29802206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.035202
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