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The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implications

Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with substantial morbidity and mortality. It causes profound changes in sarcoplasmic reticulum (SR) Ca(2+) homeostasis, including ryanodine receptor channel dysfunction and diastolic SR Ca(2+) leak, which might contribu...

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Detalhes bibliográficos
Main Authors: Dobrev, Dobromir, Voigt, Niels, Wehrens, Xander H.T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039246/
https://ncbi.nlm.nih.gov/pubmed/20943673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq324
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