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Antibody–Drug Conjugates: Pharmacokinetic/Pharmacodynamic Modeling, Preclinical Characterization, Clinical Studies, and Lessons Learned

Antibody–drug conjugates are an emerging class of biopharmaceuticals changing the landscape of targeted chemotherapy. These conjugates combine the target specificity of monoclonal antibodies with the anti-cancer activity of small-molecule therapeutics. Several antibody–drug conjugates have received...

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Bibliografische gegevens
Gepubliceerd in:Clin Pharmacokinet
Hoofdauteurs: Hedrich, William D., Fandy, Tamer E., Ashour, Hossam M., Wang, Hongbing, Hassan, Hazem E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6252075/
https://ncbi.nlm.nih.gov/pubmed/29188435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-017-0619-0
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