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A Cooperative Ternary Catalysis System for Asymmetric Lactonizations of α-Ketoesters
A general and enantioselective N-heterocyclic carbene (NHC)-catalyzed lactonization of simple enals and α-ketoesters has been discovered using a new ternary cooperative catalytic system. The highly selective annulation was achieved by using a combination of a chiral NHC, a hydrogen-bond donor, and a...
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| Publicado no: | Adv Synth Catal |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6251415/ https://ncbi.nlm.nih.gov/pubmed/30473657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adsc.201701015 |
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