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BRD4 and Cancer: going beyond transcriptional regulation

BRD4, member of the Bromodomain and Extraterminal (BET) protein family, is largely acknowledged in cancer for its role in super-enhancers (SEs) organization and oncogenes expression regulation. Inhibition of BRD4 shortcuts the communication between SEs and target promoters with a subsequent cell-spe...

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Podrobná bibliografie
Vydáno v:Mol Cancer
Hlavní autoři: Donati, Benedetta, Lorenzini, Eugenia, Ciarrocchi, Alessia
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251205/
https://ncbi.nlm.nih.gov/pubmed/30466442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0915-9
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