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BRD4 and Cancer: going beyond transcriptional regulation
BRD4, member of the Bromodomain and Extraterminal (BET) protein family, is largely acknowledged in cancer for its role in super-enhancers (SEs) organization and oncogenes expression regulation. Inhibition of BRD4 shortcuts the communication between SEs and target promoters with a subsequent cell-spe...
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| Publicado en: | Mol Cancer |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6251205/ https://ncbi.nlm.nih.gov/pubmed/30466442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0915-9 |
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