Stem cell library screen identified ruxolitinib as regulator of osteoblastic differentiation of human skeletal stem cells

BACKGROUND: Better understanding of the signaling pathways that regulate human bone marrow stromal stem cell (hBMSC) differentiation into bone-forming osteoblasts is crucial for their clinical use in regenerative medicine. Chemical biology approaches using small molecules targeting specific signalin...

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Udgivet i:Stem Cell Res Ther
Main Authors: AlMuraikhi, Nihal, Ali, Dalia, Alshanwani, Aliah, Vishnubalaji, Radhakrishnan, Manikandan, Muthurangan, Atteya, Muhammad, Siyal, Abdulaziz, Alfayez, Musaad, Aldahmash, Abdullah, Kassem, Moustapha, Alajez, Nehad M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249887/
https://ncbi.nlm.nih.gov/pubmed/30463599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1068-x
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