The Calcium Channel Blocker Bepridil Demonstrates Efficacy in the Murine Model of Marburg Virus Disease

No therapeutics are approved for the treatment of filovirus infections. Bepridil, a calcium channel blocker developed for treating angina, was identified as a potent inhibitor of filoviruses in vitro, including Ebola and Marburg viruses, and Ebola virus in vivo. We evaluated the efficacy of bepridil...

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Dades bibliogràfiques
Publicat a:J Infect Dis
Autors principals: DeWald, Lisa Evans, Dyall, Julie, Sword, Jennifer M, Torzewski, Lisa, Zhou, Huanying, Postnikova, Elena, Kollins, Erin, Alexander, Isis, Gross, Robin, Cong, Yu, Gerhardt, Dawn M, Johnson, Reed F, Olinger, Gene G, Holbrook, Michael R, Hensley, Lisa E, Jahrling, Peter B
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2018
Matèries:
Supplement Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249584/
https://ncbi.nlm.nih.gov/pubmed/29982632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy332
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