The Calcium Channel Blocker Bepridil Demonstrates Efficacy in the Murine Model of Marburg Virus Disease

No therapeutics are approved for the treatment of filovirus infections. Bepridil, a calcium channel blocker developed for treating angina, was identified as a potent inhibitor of filoviruses in vitro, including Ebola and Marburg viruses, and Ebola virus in vivo. We evaluated the efficacy of bepridil...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: DeWald, Lisa Evans, Dyall, Julie, Sword, Jennifer M, Torzewski, Lisa, Zhou, Huanying, Postnikova, Elena, Kollins, Erin, Alexander, Isis, Gross, Robin, Cong, Yu, Gerhardt, Dawn M, Johnson, Reed F, Olinger, Gene G, Holbrook, Michael R, Hensley, Lisa E, Jahrling, Peter B
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Supplement Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249584/
https://ncbi.nlm.nih.gov/pubmed/29982632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy332
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados