The Calcium Channel Blocker Bepridil Demonstrates Efficacy in the Murine Model of Marburg Virus Disease

No therapeutics are approved for the treatment of filovirus infections. Bepridil, a calcium channel blocker developed for treating angina, was identified as a potent inhibitor of filoviruses in vitro, including Ebola and Marburg viruses, and Ebola virus in vivo. We evaluated the efficacy of bepridil...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Infect Dis
Autores principales: DeWald, Lisa Evans, Dyall, Julie, Sword, Jennifer M, Torzewski, Lisa, Zhou, Huanying, Postnikova, Elena, Kollins, Erin, Alexander, Isis, Gross, Robin, Cong, Yu, Gerhardt, Dawn M, Johnson, Reed F, Olinger, Gene G, Holbrook, Michael R, Hensley, Lisa E, Jahrling, Peter B
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2018
Materias:
Supplement Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249584/
https://ncbi.nlm.nih.gov/pubmed/29982632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy332
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares