Scrophularia Atropatana Extract Reverses TP53 Gene Promoter Hypermethylation and Decreases Survivin Antiapoptotic Gene Expression in Breast Cancer Cells

BACKGROUND: In many cases of breast cancer, the aberrant methylation of TP53 gene leads to uncontrolled cell proliferation and apoptosis inhibition. Moreover, expression of oncogenes which are under the control of P53 protein could be altered. Survivin as a conspicuous example of this category plays...

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Dettagli Bibliografici
Pubblicato in:Asian Pac J Cancer Prev
Autori principali: Fakhr, Mehrdad Ghavifekr, Kahkhaie, Kolsoum Rezaie, Shanehbandi, Dariush, Hagh, Majid Farshdousti, Zarredar, Habib, Safarzadeh, Elham, Vind, Mina Abdolrahimi, Baradaran, Behzad
Natura: Artigo
Lingua:Inglês
Pubblicazione: West Asia Organization for Cancer Prevention 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6249477/
https://ncbi.nlm.nih.gov/pubmed/30256066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2018.19.9.2599
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