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A split luciferase-based probe for quantitative proximal determination of Gα(q) signalling in live cells
The earlier an activation of a G protein-dependent signalling cascade at a G protein-coupled receptor (GPCR) is probed, the less amplificatory effects contribute to the measured signal. This is especially useful in case of a precise quantification of agonist efficacies, and is of paramount importanc...
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| Foilsithe in: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Nature Publishing Group UK
2018
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6249299/ https://ncbi.nlm.nih.gov/pubmed/30464299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35615-w |
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