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CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study

Cytochrome P450 2A6 (CYP2A6) catalyzes the metabolism of nicotine and the tobacco-specific lung carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Genetic variation in CYP2A6 may affect smoking behavior and contribute to lung cancer risk. A nested case-control study of 197 lung cancer...

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Podrobná bibliografie
Vydáno v:Carcinogenesis
Hlavní autoři: Yuan, Jian-Min, Nelson, Heather H., Carmella, Steven G., Wang, Renwei, Kuriger-Laber, Jacquelyn, Jin, Aizhen, Adams-Haduch, Jennifer, Hecht, Stephen S., Koh, Woon-Puay, Murphy, Sharon E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248819/
https://ncbi.nlm.nih.gov/pubmed/28182203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx012
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