CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study

Cytochrome P450 2A6 (CYP2A6) catalyzes the metabolism of nicotine and the tobacco-specific lung carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Genetic variation in CYP2A6 may affect smoking behavior and contribute to lung cancer risk. A nested case-control study of 197 lung cancer...

詳細記述

保存先:
書誌詳細
出版年:Carcinogenesis
主要な著者: Yuan, Jian-Min, Nelson, Heather H., Carmella, Steven G., Wang, Renwei, Kuriger-Laber, Jacquelyn, Jin, Aizhen, Adams-Haduch, Jennifer, Hecht, Stephen S., Koh, Woon-Puay, Murphy, Sharon E.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
Original Manuscript
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6248819/
https://ncbi.nlm.nih.gov/pubmed/28182203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx012
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