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CYP genetic variants and toxicity related to anti-tubercular agents: a systematic review and meta-analysis

BACKGROUND: Treatment with anti-tuberculosis drugs may cause patients to experience serious adverse effects. Genetic factors, such as polymorphisms of CYP genes, may increase the likelihood of a patient experiencing such adverse drug reactions. In this systematic review and meta-analysis, we synthes...

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Dettagli Bibliografici
Pubblicato in:Syst Rev
Autori principali: Richardson, Marty, Kirkham, Jamie, Dwan, Kerry, Sloan, Derek J., Davies, Geraint, Jorgensen, Andrea L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6247669/
https://ncbi.nlm.nih.gov/pubmed/30458875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13643-018-0861-z
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