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Highly sensitive detection of DNA hypermethylation in melanoma cancer cells

Aberrant hypermethylation of CpG islands in the promoter region of tumor suppressor genes is a promising biomarker for early cancer detection. This methylation status is reflected in the methylation pattern of ctDNA shed from the primary tumor; however, to realize the full clinical utility of ctDNA...

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Publicat a:Biosens Bioelectron
Autors principals: Nesvet, Jared, Rizzi, Giovanni, Wang, Shan X.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245664/
https://ncbi.nlm.nih.gov/pubmed/30366258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bios.2018.10.018
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