Nuclear Localization of Huntingtin mRNA Is Specific to Cells of Neuronal Origin

Huntington’s disease (HD) is a monogenic neurodegenerative disorder representing an ideal candidate for gene silencing with oligonucleotide therapeutics (i.e., antisense oligonucleotides [ASOs] and small interfering RNAs [siRNAs]). Using an ultra-sensitive branched fluorescence in situ hybridization...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Rep
Main Authors: Didiot, Marie-Cécile, Ferguson, Chantal M., Ly, Socheata, Coles, Andrew H., Smith, Abigail O., Bicknell, Alicia A., Hall, Lauren M., Sapp, Ellen, Echeverria, Dimas, Pai, Athma A., DiFiglia, Marian, Moore, Melissa J., Hayward, Lawrence J., Aronin, Neil, Khvorova, Anastasia
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245656/
https://ncbi.nlm.nih.gov/pubmed/30184490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.106
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker