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Deepbinner: Demultiplexing barcoded Oxford Nanopore reads with deep convolutional neural networks

Multiplexing, the simultaneous sequencing of multiple barcoded DNA samples on a single flow cell, has made Oxford Nanopore sequencing cost-effective for small genomes. However, it depends on the ability to sort the resulting sequencing reads by barcode, and current demultiplexing tools fail to class...

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Vydáno v:PLoS Comput Biol
Hlavní autoři: Wick, Ryan R., Judd, Louise M., Holt, Kathryn E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6245502/
https://ncbi.nlm.nih.gov/pubmed/30458005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006583
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