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DeepNano: Deep recurrent neural networks for base calling in MinION nanopore reads

The MinION device by Oxford Nanopore produces very long reads (reads over 100 kBp were reported); however it suffers from high sequencing error rate. We present an open-source DNA base caller based on deep recurrent neural networks and show that the accuracy of base calling is much dependent on the...

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Vydáno v:PLoS One
Hlavní autoři: Boža, Vladimír, Brejová, Broňa, Vinař, Tomáš
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459436/
https://ncbi.nlm.nih.gov/pubmed/28582401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178751
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