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ROLES FOR FOXO1 AND FOXO3 IN REGULATION OF CANCER AND LIFESPAN IN DIETARY-RESTRICTED MICE
Forkhead box O (Foxo) transcription factors may be involved in the salutary effect of dietary restriction (DR). We investigated roles for Foxo1 and Foxo3 in regulation of cancer and lifespan in mice. The preventive effect of DR on cancer was diminished in Foxo1-knockout heterozygotic (+/–) mice, alt...
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| Pubblicato in: | Innov Aging |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6245164/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.1544 |
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