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Synthesis of pyrrolidine-based hamamelitannin analogues as quorum sensing inhibitors in Staphylococcus aureus

Interfering with bacterial cell-to-cell communication is a promising strategy to combat antimicrobial resistance. The natural product hamamelitannin and several of its analogues have been identified as quorum sensing inhibitors. In this paper the synthesis of pyrrolidine-based analogues of a more le...

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Dettagli Bibliografici
Pubblicato in:Beilstein J Org Chem
Autori principali: Bouton, Jakob, Van Hecke, Kristof, Rasooly, Reuven, Van Calenbergh, Serge
Natura: Artigo
Lingua:Inglês
Pubblicazione: Beilstein-Institut 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6244240/
https://ncbi.nlm.nih.gov/pubmed/30498532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.260
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