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Treatment of Staphylococcus aureus Biofilm Infection by the Quorum-Sensing Inhibitor RIP

The quorum-sensing inhibitor RIP inhibits staphylococcal TRAP/agr systems and both TRAP- and agr-negative strains are deficient in biofilm formation in vivo, indicating the importance of quorum sensing to biofilms in the host. RIP injected systemically into rats has been found to have strong activit...

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Detalhes bibliográficos
Main Authors: Balaban, Naomi, Cirioni, Oscar, Giacometti, Andrea, Ghiselli, Roberto, Braunstein, Joel B., Silvestri, Carmela, Mocchegiani, Federico, Saba, Vittorio, Scalise, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891383/
https://ncbi.nlm.nih.gov/pubmed/17371825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01097-06
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