Treatment of Staphylococcus aureus Biofilm Infection by the Quorum-Sensing Inhibitor RIP

The quorum-sensing inhibitor RIP inhibits staphylococcal TRAP/agr systems and both TRAP- and agr-negative strains are deficient in biofilm formation in vivo, indicating the importance of quorum sensing to biofilms in the host. RIP injected systemically into rats has been found to have strong activit...

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Bibliographic Details
Main Authors: Balaban, Naomi, Cirioni, Oscar, Giacometti, Andrea, Ghiselli, Roberto, Braunstein, Joel B., Silvestri, Carmela, Mocchegiani, Federico, Saba, Vittorio, Scalise, Giorgio
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891383/
https://ncbi.nlm.nih.gov/pubmed/17371825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01097-06
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