Treatment of Staphylococcus aureus Biofilm Infection by the Quorum-Sensing Inhibitor RIP

The quorum-sensing inhibitor RIP inhibits staphylococcal TRAP/agr systems and both TRAP- and agr-negative strains are deficient in biofilm formation in vivo, indicating the importance of quorum sensing to biofilms in the host. RIP injected systemically into rats has been found to have strong activit...

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Autori principali: Balaban, Naomi, Cirioni, Oscar, Giacometti, Andrea, Ghiselli, Roberto, Braunstein, Joel B., Silvestri, Carmela, Mocchegiani, Federico, Saba, Vittorio, Scalise, Giorgio
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1891383/
https://ncbi.nlm.nih.gov/pubmed/17371825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01097-06
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